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USMLE USMLE : United States Medical Licensing Examination

USMLE real exams

Exam Code: USMLE

Exam Name: United States Medical Licensing Examination

Updated: Sep 18, 2026

Q & A: 400 Questions and Answers

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About USMLE USMLE Exam

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Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.

USMLE Step 2 is a one-day (8 hours) exam. Similar to the Step 1, the test items are divided into blocks, and test item formats vary within each block, with the total number of exam questions equaling to 355.

Reference: http://www.usmle.org/step-1/#question-formats

USMLE USMLE Exam Syllabus Topics:

SectionObjectives
Multisystem Processes and Disorders- Systemic Conditions
  • 1. Neoplasia
  • 2. Infectious Diseases
  • 3. Nutrition
General Principles- Foundational Medical Sciences
  • 1. Genetics
  • 2. Behavioral Sciences
  • 3. Physiology
  • 4. Pathology
  • 5. Immunology
  • 6. Biochemistry
  • 7. Microbiology
  • 8. Pharmacology
Respiratory System- Pulmonary Medicine
  • 1. Lung Diseases
  • 2. Airway Disorders
Endocrine System- Hormonal Regulation and Disease
  • 1. Pituitary Disorders
  • 2. Thyroid Disorders
  • 3. Adrenal Disorders
Reproductive System- Male and Female Reproductive Health
  • 1. Reproductive Physiology
  • 2. Reproductive Disorders
Renal and Urinary System- Kidney and Urinary Disorders
  • 1. Renal Physiology
  • 2. Renal Pathology
Central and Peripheral Nervous Systems- Neurologic Disorders
  • 1. Neuroanatomy
  • 2. Neurologic Diseases
  • 3. Neuropathology
Musculoskeletal System- Bones, Joints, and Muscles
  • 1. Rheumatologic Diseases
  • 2. Orthopedic Disorders
Hematopoietic and Lymphoreticular Systems- Blood and Immune Disorders
  • 1. Coagulation Disorders
  • 2. Leukemias and Lymphomas
  • 3. Anemias
Skin and Related Connective Tissue- Dermatologic Conditions
  • 1. Skin Neoplasms
  • 2. Inflammatory Skin Disorders
Human Development- Growth and Development
  • 1. Embryology
  • 2. Developmental Abnormalities
Gastrointestinal System- Digestive System Disorders
  • 1. Gastrointestinal Pathology
  • 2. Liver Disease
Cardiovascular System- Cardiac and Vascular Disorders
  • 1. Vascular Pathology
  • 2. Heart Disease

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